LY75/DEC-205 anticorps (Biotin)

N° du produit ABIN111869

L’anticorps Rat Monoclonal anti-LY75/DEC-205 a été validé pour FACS et IHC (fro). Il convient pour détecter LY75/DEC-205 dans des échantillons de Souris.

Aperçu rapide pour LY75/DEC-205 anticorps (Biotin) (ABIN111869)

Antigène: LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp LY75/DEC-205 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: NLDC145

Détail du produit anti-LY75/DEC-205 anticorps (Biotin)

Specificité: Reacts with nonlymphoid dendritic cells: interdigitating cells (IDC), veiled cells and Langerhans cells, thymic epithelial cells. Monoclonal antibody NLDC-145 identifies Ia positive interdigitating cells, veiled cells and Langerhans cells of the skin and their in vitro counterparts. The antigen is expressed at high levels by dendritic cells and thymic epithelial cells. The antigen detected by NLDC-145 is an integral membrane glycoprotein with an apparent mass of 205 kDa, also known as DEC-205.

Purification: Affinity Chormatography.

Immunogène: Mouse lymph node tissue.

Isotype: IgG2a

Information d'application

Indications d'application: Immunohistochemistry on Acetone Fixed Frozen Sections: 3 μg/mL (1/300). Recommended Positive Control: Mouse Spleen. Has been described to work in FACS.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 0.5 mL distilled water.

Concentration: 0.3 mg/mL

Buffer: PBS, pH 7.2 containing 5 mg/mL BSA as stabilizer and 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted Prior to and following reconstitution at 2-8 °C. DO NOT FREEZE! This antibody is photosensitive and should be protected from light.

Détails sur LY75/DEC-205

Antigène: LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

Autre désignation: CD205 / DEC-205

Sujet: Mouse CD205, also known as DEC-205 (dendritic and epithelial cells, 205 kDa). CD205 is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. DEC-205 is apparently a receptor involved in antigen-processing by dendritic cells.Synonyms: C-type lectin domain family 13 member B, CLEC13B, DEC205, LY75, Lymphocyte antigen 75, gp200-MR6

ID gène: 17076

NCBI Accession: NP_038853

UniProt: Q60767